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• Patients generally develop left ventricular hypertrophy, which may be related to hypertension, another adverse effect of AAS.
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Anabolic Steroids, Acute Myocardial Infarction And Polycythemia: A Case Report And Review Of The Literature

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However, testosterone in physiologic doses may even be beneficial in patients with angina , have larger ischemic thresholds and improved quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and increases coronary blood flow in men with established coronary artery illness . Therefore, an interaction of endogenous factors webcams sex of the patient’s risk profile as properly as the testosterone dosing could also be issues of whether opposed events occur. Erythrocytosis has been reported as a potential impact of testosterone, which may be useful in patients with anemia.

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We report a case of an acute ST-segment elevation myocardial infarction in a patient with traditional cardiac danger components using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this patient additionally had polycythemia, probably secondary to high-dose testosterone. The patient underwent successful percutaneous intervention of the right coronary artery. Physicians and patients ought to pay attention to the clinical penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996). Moreover, a component of endothelial dysfunction has been proposed, which may contribute to abnormal vessel reactivity.

Case Report

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Patients also may be taking concomitant stimulants, similar to ephedra, which might confound knowledge and the potential for antagonistic occasions. It is likely that the frequency of cardiac events is underreported within the medical literature. Moreover, testosterone has been used in the treatment of reduced muscle mass and bone density in addition to anemia. The role testosterone may play in the improvement of cardiovascular disease has more and more turn out to be the topic of current interest . Supraphysiologic doses of anabolic-androgenic steroids , which embody more than 30 natural and artificial derivatives of testosterone, could cause a large spectrum of medical sequalae. Supplemental or physiologic doses of testosterone have seen expanded use in medical practice lately. Other widespread potential antagonistic results embrace infertility, hepatotoxicity, psychological abnormalities, and gynecomastia .

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